Saturday, 3 March 2012

Open Source/Crowd Source Cancer research



In today's post, I'd like to discuss the idea of open-source/crowd-source researches, and optimistically suggest/promote the adoption of this philosophy in future researches. In many fields of study, we've seen the concept of open source and crowdsourcing adopted and successfully achieving great development and solutions to seemingly unsolvable problems. In the computer science industry, we've seen major successes in the development of computer software, where applications such as OpenOffice, GIMP (More of these on the previous post) help reduce fees to use/modify these applications, and drive development of software forward. Other examples include Apache (http://httpd.apache.org/) and Linux operating systems (https://www.linux.com/).

In light of these successes, it has been suggested in the field of medicine to adopt the idea of open-source reseach and crowdsourcing. In particular, I'd like to address the issues of current (and past) cancer researches:

Personally, I believe that this reporter has blown this out of proportion, but there are some key issues that are true here: The profits are little to none since in most jurisdictions, chemical patents are hard to protect. It was also mentioned that Dr. Evangelos Michelakis had a “hard time getting anybody to pay attention to this because there's no money to be made in this,” but then he mentioned the possibility of insurance companies to invest in this promising research, and the response was that there are many walls that make it hard for insurance companies to invest in these researches.

The general issues in cancer researches are lack of profit and no support, which brings the following question:
Is There Really a Conspiracy to Suppress Cancer Cures?

Here is Jay Bradner's view on making cancer researches open source:


(This video is both in YouTube and in Ted Talks)

Jay Bradner is a researcher in Harvard and Dana Farber, and he talks about his progress in cancer research. In his speech, he mentioned that a drug company would probably "keep this a secret until they turn the prototype drug into an active pharmaceutical substance," and they just did the opposite. They published a paper describing their findings explaining how to make the chemical compound that they've made. It ultimately made the perfect competitive environment. The openness of this cancer research is it's greatest strength, and I believe that with more specialists brought into this research, we can speed the progress of making better cancer treatment and discovering more cancer cures.

Jay Bradner is basically giving the "secret" away for the better of progress in curing cancer. With so many labs and pharmaceutical companies in the world we can surely agree that this is the perfect environment for open source cancer researches. I believe that there is great potential in this philosophy, and making the cancer research open source will ultimately help subvert cancer.